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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2016, Volume : 4, Issue : 2
First page : (218) Last page : (220)
Article doi: http://dx.doi.org/10.18782/2320-7051.2258

In vitro Brine Shrimp Lethality Bioassay of Aqueous Extract of Bark of Magnifera indica

Shalaka V. Patil*, Sandip R. Kane and Chandrakant S. Magdum
Rajarambapu College Of Pharmacy, Kasegaon, Maharashtra, India
*Corresponding Author E-mail: spshalaka2022@gmail.com
Received: 1.04.2016  |  Revised: 13.04.2016   |  Accepted: 15.04.2016  

Abstract
Mangos belong to the genus Mangifera of the family Anacardiaceae. The genus Mangifera contains several species that bear edible fruit. Most of the fruit trees that are commonly known as mangos belong to the species Mangifera indica. it has also been used for its medicinal value. In Samoa, a bark infusion has been a traditional remedy for mouth infections in children (pala gutu), and in Tonga, infusions of leaves of mango, the orange (Citrus sinensis), and other species are used to make a potion to treat relapse sickness (kita). In India, a drink made from unripe mango fruit is used as a remedy for exhaustion and heat stroke. Half-ripe fruit eaten with salt and honey is used for a treatment of gastro-intestinal disorders, bilious disorders, blood disorders, and scurvy. Diabetes has been treated with a drink made from the infusion of fresh mango leaves. Dried mango seed ground into flour is used to treat diarrhea. Diarrhea and throat disorders are treated by gargling bark extracts mixed with water. Fruit sap has been used to treat the pain of bee and scorpion stings1. Many of the traditional Indian medicinal uses of mango involve eating unripe fruit. The present work was accomplished to explore the cytotoxic potential of aqueous extract of Mangifera indica using brine shrimp lethality bioassay method. In this methods, Mangifera indica showed a significant activity. The cytotoxic activity of the extract was moderate having LC50 value of 5.05 μg/ml.

Key words: Brine shrimp, Cytotoxicity, Bark of Mangifera indica, Anacardiaceae.

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782


Cite this article: Patil, S.V., Kane, S.R. and Magdum, C.S., In vitro Brine Shrimp Lethality Bioassay of Aqueous Extract of Bark of Magnifera indica, Int. J. Pure App. Biosci.4(2): 218-220 (2016). doi: http://dx.doi.org/10.18782/2320-7051.2258