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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2016, Volume : 4, Issue : 4
First page : (69) Last page : (76)
Article doi: http://dx.doi.org/10.18782/2320-7051.2327

Exertion of Gold Nanoparticles Synthesis in Extract of Garcinia combogia Leaves, Evaluation of its Total Phenolic Content and its Distinct Antioxidant Activity

B. Nithya1* and A. Jayachitra2
1Research Scholar, Research and Development Centre, Bharathiyar University, Tamil Nadu, India
2Assistant Professor, Department of Plant Biotechnology, School of Biotechnology
Madurai Kamaraj University, Tamil Nadu, India
*Corresponding Author E-mail: nithya.hannah@gmail.com
Received: 1.07.2016  |  Revised: 12.07.2016   |  Accepted: 15.07.2016  

Abstract
As the green nano synthesis is flourishing constantly it is indispensable to incorporate   nanotechnology in medicine. Prelimiary studies in the leaves of Garcinia combogia have shown the presence of bioactive secondary metabolites. The present investigation discloses the synthesis gold nano particle using the leaves of Garcinia combogia and its antioxidant   property.  The total phenolic contents (TPC) were determined by the Folin- Ciocalteu method. The free radicalscavenging activity of the synthesized nanoparticles was ascertained by the DPPH assay, Nitric oxide (NO) radical scavenging, Superoxide (SO) radical scavenging and Hydrogen Peroxide scavenging. The gold nano particles of Garcinia combogia exhibit apparent scavenging activity and excellent antioxidant activity.The phenolic compounds that exist in Garcinia combogia have the potential to function as antioxidants by scavenging or stabilizing the free radicals involved in oxidative processes.

Key words: Garcinia combogia, nano particles, TPC. DPPH assay, NO, SO Scavenging

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782


Cite this article: Nithya, B. and Jayachitra, Exertion of Gold Nanoparticles Synthesis in Extract of Garcinia combogia Leaves, Evaluation of its Total Phenolic Content and its Distinct Antioxidant Activity, Int. J. Pure App. Biosci.4(4): 69-76 (2016). doi: http://dx.doi.org/10.18782/2320-7051.2327