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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2017, Volume : 5, Issue : 5
First page : (1343) Last page : (1351)
Article doi: http://dx.doi.org/10.18782/2320-7051.5931

Review on Rabies with Emphasis on Recent Diagnostic Assays

Piyush Tomar1*, Somesh Banerjee2, Praveen Kumar3 and Pankaj Gunwant4
1Department of Veterinary Public Health and Epidemiology
2Department of Veterinary Microbiology
3Departemnt of Veterinary Medicine
4Department of Veterinary Gynaecology and Obstetrics, College of Veterinary Sciences
Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar – 125 004
*Corresponding Author E-mail: tomarvety@gmail.com
Received: 20.09.2017  |  Revised: 23.10.2017   |  Accepted: 26.10.2017  

 ABSTRACT

Rabies is a zoonotic and acute viral disease of the central nervous system (CNS) caused by rabies virus of the genus Lyssavirus and family Rhabdoviridae. All warm-blooded animals are susceptible for this disease. Around 2000 peoples die every year in India due to rabies. This disease is mainly transmitted by biting of rabid animals. Main reservoirs for rabies are wildlife like skunks, raccoons, bats and foxes. This virus causes neurological signs and death. Incubation period of rabies virus varies from 14 days to 6 years. Rapid diagnosis is important for taking prevention and control measures against rabies. Conventional and rapid methods for diagnosis of rabies are Seller’s staining and histopathological technique. The gold standard test for diagnosis of rabies as per OIE is direct immunofluoroscent test in brain tissues of dogs. For routine diagnosis polymerase chain reaction (PCR) and Mouse inoculation test (MIT) are also commonly used. This review highlights the recent diagnostic tests which are commonly in use for diagnosis of rabies.

Key words: Rabies, CNS, Disease, MIT, immunofluoroscent test.

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782

Cite this article: Tomar, P., Banerjee, S., Kumar, P. and Gunwant, P., Review on Rabies with Emphasis on Recent Diagnostic Assays, Int. J. Pure App. Biosci.5(5): 1343-1351 (2017). doi: http://dx.doi.org/10.18782/2320-7051.5931