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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2018, Volume : 6, Issue : 5
First page : (911) Last page : (920)
Article doi: :

Resistance Pattern of Staphylococcus aureus Isolated from Subclinical Mastitis towards Beta-Lactam Group of Antimicrobials

Karande Vikas Vasant1*, Lengare Ashali Shankarrao2 and Gatne Madhumanjiri Mukulesh3

1Assistant Professor, Department of pharmacology and Toxicology, Krantisinh Nana Patil college of Veterinary Science, Shirwal, taluka- Khandala, Dist- Satara-412801
2Livetock development Officer, Veterinary Dispensary, Mohopada, Khalapur, Raigad
3Retd Professor, Department of Pharmacology and Toxicology, Bombay Veterinary College, Parel, Mumbai
*Corresponding Author E-mail:

Received: 2.09.2018  |  Revised: 30.09.2018   |  Accepted: 7.10.2018



Antimicrobial resistance (AMR) is when organisms become irresponsive to the commonly used antimicrobials for which previously they were susceptible. Many organisms are responsible to cause mastitis in dairy animals. Beta-lactam group of antimicrobials are most widely used in the treatment of mastitis and other animal diseases. Therefore present study was planned to investigate selected beta-lactam antimicrobials susceptibility pattern against S. aureus organisms isolated from bovine subclinical mastitis.  S. aureus grown on selective media and tested for susceptibility pattern on Muller-Hinton Agar. Total 168 S. aureus isolates were tested and showed different resistance patterns. Highest Resistance was observed to Ampicillin (57.14%) and Amoxicillin (56.54%). Greater sensitivity was observed to cephalosporins and other beta-lactams when used along with beta-lactamase inhibitors. It is suggested to observe the sensitivity pattern while treating animal diseases in order to minimize the resistance raised due to use of wrong and inadvertent use of these magic bullets. 

Key words: Resistance, Beta-lactams, S. aureus

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Cite this article  Karande, V.V., Lengare, A. S., and Gatne, M.M., Resistance Pattern of Staphylococcus aureus Isolated from Subclinical Mastitis towards Beta-Lactam Group of Antimicrobials, Int. J. Pure App. Biosci.6(5): 911-920 (2018). doi: