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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2018, Volume : 6, Issue : 6
First page : (789) Last page : (797)
Article doi: :

Metallic Nanoparticles Playacting as Bactericidal Agent

Gargibala Satpathy1, E. Manikandan1,2 and Srinisha Jagathrakshakan1 *

Central Research Laboratory, BIHER, Bharath University, Chennai-600073, Tamil Nadu, India
Solid-State Nanoscale Laboratory, Dept. of Physics, Thiruvalluvar University, Vellore, India
*Corresponding Author E-mail:
Received: 1.11.2018  |  Revised: 6.12.2018   |  Accepted: 15.12.2018  



Here, we present a review of the antibacterial effects of metal nanomaterial. Proposed antibacterial mechanisms and possible toxicity to bacterial cells. Nanoparticles (NPs) are increasingly used to target bacteria as an alternative to antibiotics. Nanotechnology may be particularly advantageous in treating bacterial infections. Currently accepted mechanisms include oxidative stress induction, metal ion release, and non-oxidative mechanisms. There is some evidence that nanoparticles can directly damage bacteria cell membranes, leakage of cellular content and disruption DNA replication. In this review, we discuss the antibacterial mechanisms of NPs against bacteria and the factors that are involved. We mainly emphasize on zinc, gold and cobalt material their synthesis and mechanism of bactericide.

Key words: Antimicrobial activity, Nanoparticles, Metals, Bacteria, Oxidative stress.

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Cite this article: Satpathy, G., Manikandan, E. and Jagathrakshakan, S., Metallic Nanoparticles Playacting as Bactericidal Agent, Int. J. Pure App. Biosci.6(6): 789-797 (2018). doi: