INTERNATIONAL JOURNAL OF PURE & APPLIED BIOSCIENCE
ISSN : 2320-7051
International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2018, Volume : 6, Issue : 6
First page : (428) Last page : (434)
Article doi: : http://dx.doi.org/10.18782/2320-7051.7174
Study on the Impact of Groundwater-Minerals of Urban-Dhubri on Transamination and Mobilization of Thyroid Hormones in Liver of Heteropneustes fossilis Bloch
Department of Zoology, Bholanath College, Dhubri-783324, (Assam)*
*Corresponding Author E-mail: email@example.com
Received: 2.11.2018 | Revised: 13.12.2018 | Accepted: 17.12.2018
This study coved observations of Lipid Peroxide (LPO) in liver, Aspartate Transferase (AST) and Alanine Transferase (ALT) activities in liver and blood serum; amount of Essential and Non-essential amino acids in liver; Tri-iodothyronine (T3), Tetra-iodothyronine (T4) and Thyroid Stimulating Hormone (TSH) in liver and blood serum of Heteropneustes fossilis Bloch exposed to sublethal concentrations of groundwater-minerals of Urban-Dhubri.
LC50 values (for 96 hours) for the ground minerals separated from waters of Balur Char area was determined as 61.8 ± 0.39 ppm, for those of D. K. Road was 47.4 ± 0.27 ppm and for those of R. K. Mission Road was 66.9 ± 0.28 ppm. Minerals from the water of R. K. Mission Road was found to be the most toxic and studies carried using the groundwater minerals of R. K. Mission Road.
The study revealed that sub-lethal exposure to groundwater mineral lead to increased Lipid Peroxidation in liver, decreased activities of AST and ALT in liver and increased activities of these enzymes in blood serum. Hypothyroidic condition with decreased T3 and T4 contents and increased TSH content were observed both in liver and blood serum on treatment. Increased amount of essential amino acids and decreased amount of non-essential amino acids were marked in liver on exposure.
Key words: Exposure, Fish, Lipid-peroxide, Transamination, Hypothyroidic.
Full Text : PDF; Journal doi : http://dx.doi.org/10.18782
Cite this article: Sarma, S., Study on the Impact of Groundwater-Minerals of Urban-Dhubri on Transamination and Mobilization of Thyroid Hormones in Liver of Heteropneustes fossilis Bloch, Int. J. Pure App. Biosci.6(6): 428-434 (2018). doi: http://dx.doi.org/10.18782/2320-7051.7174