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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2019, Volume : 7, Issue : 2
First page : (446) Last page : (454)
Article doi: :

Impact of Long Term Exposure to Petroleum Products on Hematological Parameters in Petrol Pump Workers of Dehradun Region

Deepali Joshi1*, Gyanendra Awasthi2 and T. K. Mandal3

1Research Scholar, 2Associate Professor, 3Faculty,
1,3ICFAI University, Dehradun
2Department of Biochemistry, Dolphin (PG) Institute of Bio medical & Natural Sciences, Dehradun
*Corresponding Author E-mail:
Received: 7.03.2019 | Revised: 12.04.2019 | Accepted: 19.04.2019  




Petroleum products are used for various reasons by human beings at homes, in manufacturing and petrochemical industries. The individuals most frequently exposed are those working in enterprises concerned with petrol and diesel, like petrol pumps. Chronic exposure to these compounds causes CNS depression and affects the kidney, liver, blood and systems. Hence, the present study was undertaken to assess the extent of damage caused by the chronic inhalation of petrol fumes on the hematopoietic system of human cases. The study was carried out on adult human subjects in Dehradun region.150 fuel attendants were included in the study. These were divided into three groups based on years of working experience in petrol pumps. The complete blood count was performed in department of Biochemistry, Dolphin (PG) Institute of Biomedical and Natural Sciences, Dehradun (UK) using KX-21 sysmex cell counter. Data pertaining to different parameters of  hematology, were recorded from 50 subjects each from three groups based on years of working experience in petrol pumps  viz 1 – 5 yrs, 6 – 10 yrs and >10yrs. The data was analyzed applying one way ANOVA Technique. The main factor was the categories of years of experience at petrol pumps. The Statistical Package Genstat -32 was used.
We found significant decrease in hemoglobin, RBC count, PCV, MCHC and platelets with respect to years of exposure, other parameters such as TLC, DLC, MCV, and MCH were varying insignificantly with respect to years of working experience in petrol pumps. All the parameters were within normal limits. This concludes that chronic exposure to petroleum fumes has adverse effects on human hematopoietic system, leading to bone marrow depression and resultant pancytopenia.

Key words: Haemoglobin, Petroleum products, TLC, MCHC, MCH

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Cite this article: Joshi, D., Awasthi, G. and Mandal, T. K., Impact of long term exposure to petroleum products on hematological parameters in petrol pump workers of Dehradun region, Int. J. Pure App. Biosci.7(2): 446-454 (2019). doi: