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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2019, Volume : 7, Issue : 2
First page : (568) Last page : (573)
Article doi: : http://dx.doi.org/10.18782/2320-7051.7331

Evaluation of Anthelmintic Efficacy of Ethanolic Extract of Azadirachta indica in Goats

Avinash M. Gadhave¹, Vikas V Karande^2*, B.C. Ghumare³, K Kundu⁴, S. N. Jadhav⁵ and P. P. Mhase⁶

¹M.V.Sc scholar, Department of Pharmacology and Toxicology, ^2*,3Assistant Professor, Department of Pharmacology and Toxicology, ⁴Department of Parasitology, 5Assistant Professor Department of Biochemistry,
Krantisinh Nana Patil College of Veterinary Science, Shirwal Dist- Satara
6Assistant Professor, Department of Microbiology, Krantisinh Nana Patil College of Veterinary Science,
Shirwal Dist- Satara, Bombay Veterinary College, Parel, Mumbai -400012, India
*Corresponding Author E-mail: drvikas111081@gmail.com
Received: 4.02.2019 | Revised: 27.02.2019 | Accepted: 6.03.2019  

 ABSTRACT

In India, Goat is considered as a ‘poor mans cow’ and the Population of goats is about 135.17 millions, which is 26.40 % of total livestock population in India out of these Maharashtra share 6.24% involving about 79.71 lakh as per 19th census of India. Helmintic infection of Gastrointestinal (GI) tract is one of the major causes of decreased productivity in goat worldwide, particularly under grazing conditions. GI parasitic infection in goat is characterized clinically by anemia, emaciation, enteritis, dehydration and death in kids. Further helminth infections are treated with chemotherapeutic agents like benzimidazole (albendazole, fenbendazole and oxfendazole), imidazothiazole (levamisole) and avermectins or milbemycins (ivermectin, doramectin and moxidectin). However the cost effectiveness and increased resistance to these drugs putting the huge burden on economics of goat production. Hence in present study the anthelmintic effectiveness of Azadirachta indica was investigated in goats. Ethanolic extract of A. indica was fed to the goats at the rate of 200mg/kg subsequently for five days and compared anthelmintic efficacy with fenbedazole. After 28th day of study ethanolic extract of plant and standard drug showed significant reduction in eggs per gram of the helminths compared to control group.

Key words: A. indica, Benzimidazole, Anthelmintic, Goats.

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782

Cite this article: Gadhave, A.M., Karande, V.V., Ghumare, B.C., Kundu, K., Jadhav, S.N. and Mhase, P. P., Evaluation of Anthelmintic Efficacy of Ethanolic Extract of Azadirachta indica in Goats, Int. J. Pure App. Biosci. 7(2): 568-573 (2019). doi: http://dx.doi.org/10.18782/2320-7051.7331