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Indian Journal of Pure & Applied Biosciences (IJPAB)
Year : 2020, Volume : 8, Issue : 6
First page : (146) Last page : (151)
Article doi: : http://dx.doi.org/10.18782/2582-2845.8424

Isolation of β - amyrin from the Stems of Solenostemma argel, Elucidation of its Structure and Determination of Antimicrobial Activity

Noora T. Gipreel^1*, M. E. M. Abdelaziz², A. E. M. Saeed³, Tagelsir I. M. Idris⁴ and Mohamed Osman A.^4
1,2,3Department of chemistry, College of Science, Sudan University of Science and Technology
⁴Department of Horticulture, Sudan University of Science and Technology, Sudan
*Corresponding Author E-mail: anoorataha@gmail.com
Received: 15.10.2020 | Revised: 18.11.2020 | Accepted: 25.11.2020 

 ABSTRACT

New triterpenoid alcohol was isolated from the active fraction of the extract of stems of Solenostemma argel and elucidated by physical (m. p.) and spectroscopic methods (UV, IR, 1H and 13CNMR and EIMS), as β-amyrin. The cup-plate agar diffusion method was used to estimate the inhibition of the activity of four types of bacteria: two Gram-positive Bacillus subtilis (B.s) and Staphylococcus aureus (S.a), and two Gram-negative Escherichia coli (E.c) and Pseudomonas aeruginosa (p.s), as well as two types of fungal Aspergillus niger (A. n) and Candida albicans (C. a). Among the other solvents used for the extractions (ethyl acetate, n-hexane, n-butanol and water), chloroform extract demonstrated the highest antimicrobial activity.

Keywords: Microbial growth, inhibition zone, β-amyrin, Solenostemma argel.

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782

Cite this article: Gipreel, N.T., Abdelaziz, M.E.M., Saeed, A.E.M., Idris, T.I.M., & Osman, M.A. (2020). Isolation of β-amyrin from the Stems of Solenostemma argel, Elucidation of its Structure and Determination of Antimicrobial Activity, Ind. J. Pure App. Biosci. 8(6), 146-151. doi: http://dx.doi.org/10.18782/2582-2845.8424