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Indian Journal of Pure & Applied Biosciences (IJPAB)
Year : 2018 , Volume 6, Issue 6
Page No. : 789-797
Article doi: : http://dx.doi.org/10.18782/2320-7051.7182

Metallic Nanoparticles Playacting as Bactericidal Agent

Gargibala Satpathy¹, E. Manikandan^1,2* and Srinisha Jagathrakshakan¹

¹Central Research Laboratory, Sree Balaji Medical College & Hospital (SBMCH), Bharath Institute for Higher Education & Research (BIHER), Chrompet, Bharath University, Chennai-600073, Tamil Nadu, India
²Solid-State Nanoscale Laboratory, Dept. of Physics, TUCAS Campus, Thennangur-604408, Thiruvalluvar University, Vellore, India
^*Corresponding Author E-mail: maniphysics@gmail.com
Received: 1.11.2018 | Revised: 6.12.2018 | Accepted: 15.12.2018

ABSTRACT

Here, we present a review of the antibacterial effects of metal nanomaterial. Proposed antibacterial mechanisms and possible toxicity to bacterial cells. Nanoparticles (NPs) are increasingly used to target bacteria as an alternative to antibiotics. Nanotechnology may be particularly advantageous in treating bacterial infections. Currently accepted mechanisms include oxidative stress induction, metal ion release, and non-oxidative mechanisms. There is some evidence that nanoparticles can directly damage bacteria cell membranes, leakage of cellular content and disruption DNA replication. In this review, we discuss the antibacterial mechanisms of NPs against bacteria and the factors that are involved. We mainly emphasize on zinc, gold and cobalt material their synthesis and mechanism of bactericide.

Key words: Antimicrobial activity, Nanoparticles, Metals, Bacteria, Oxidative stress.

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782/2320-7051.7182

Cite this article:

Satpathy, G., Manikandan, E. and Jagathrakshakan, S., Metallic Nanoparticles Playacting as Bactericidal Agent, Int. J. Pure App. Biosci. 6(6): 789-797 (2018). doi: http://dx.doi.org/10.18782/2320-7051.7182

No. 772, Basant Vihar, Kota

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