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Indian Journal of Pure & Applied Biosciences (IJPAB)
Year : 2019 , Volume 7, Issue 3
Page No. : 15-24
Article doi: : http://dx.doi.org/10.18782/2320-7051.7464
The Hepato-Renal Protective Effect of Nelumbo nucifera Gaertn Seeds against Carbon Tetra Chloride Toxicity in Rats
Amber Ayaz Memon, Lubna Naz*, Sakina Shabbir and Zoha Khan
Department of Physiology, University of Karachi, Karachi, Pakistan
*Corresponding Author E-mail: lunasaf@yahoo.com
Received: 13.04.2019 | Revised: 20.05.2019 | Accepted: 26.05.2019
ABSTRACT
Background: Hypothyroidism is one of the most common forms of thyroid dysfunction. It is influence on the value of electrolytes. Objective The study was designed to find out the effect of hypothyroidism on some electrolytes and total calcium levels. Patients and materials: A total of thirty known cases of hypothyroidism and twenty age and.sex match controls were selected. Blood samples were taken from both (patients and control) to evaluate thyroid stimulating hormone (TSH) by ELISA method, as well as potassium, sodium and calcium were measured automated by Genex Elyte 4 device. Results: It was found the levels of total calcium and sodium were decreased significantly (p<0.05) cases as compare with control group, while the level of potassium was decreased no significantly (p> 0.05) in cases than control. Also, the results were indicated to a significant negative correlation between serum TSH value and calcium level in patients. Increased the TSH levels, lower will be the levels of serum calcium, sodium and potassium levels. Conclusion: It was concluded the level of total calcium decreased significantly in person with hypothyroid as well as sodium was decreased.
Key words: Hypothyroid, Calcium, Electrolyte, Sodium.
Full Text : PDF; Journal doi : http://dx.doi.org/10.18782/2320-7051.7464
Cite this article:
Memon, A.A., Naz, L., Shabbir, S., and Khan, Z., The Hepato-Renal Protective Effect of Nelumbo nucifera Gaertn Seeds Against Carbon Tetra Chloride Toxicity In Rats, Int. J. Pure App. Biosci. 7(3): 15-24 (2019). doi: http://dx.doi.org/10.18782/2320-7051.7464
