Archives

The present study deals with the polar and non polar stem extracts of Caralluma fimbriyata. In this study
polar (Methanol, Ethanol, Water) and non-polar (Chloroform, Petroleum Ether) solvent extracts of
Caralluma fimbriyata were investigated for their phytochemical and antimicrobial activity.
Phytochemical analysis revealed the presence of the Tannins, phenols, alkaloids, flavonoids, terpenoids,
glycosides and steroids. Polar extracts showed more phytochemicals than the non polar extracts. The
glycosides are found to be present in non polar extracts that are absent in the polar solvent. The
microorganisms employed were E.coli, Streptococcus aureus, Streptococcus epidermidis, Klebsiella,
Bacillus subtilis and Proteus. Among the three aqueous, ethanol and methanolic extracts were found to
more active towards the organisms tested than the non polar extracts. The analysis revealed maximum
activity of polar solvent against bacteria in order of the Proteus, staphylococcus aureus, Bacillus Sp.,
E.coli, Streptococcus epidermidis, Klebsiella Sp., Whereas non polar solvent extracts showed their
maximum activity on bacteria in order to Staphylococcus aureus, Bacillus, E.coli, Proteus, Klebsiella,
Streptococcus epidermidis. Due to the presence of various active phytochemicals present in Caralluma
fimbriyata may be attribute to the broad spectrum inhibition zone against microorganisms, which may be
their individual or combined action
Key words: Caralluma fimbriyata, Polar, non polar, Stem extracts, Antibacterial.