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More than 3000 plant species that have reportedly been used in the treatment of cancer and other
diseases. Plant derived compound have played an important role in the development of several
clinically useful anticancer agents. Catharanthus roseus is an important medicinal plant of the
Apocynacae family. Catharanthus roseus plant leaves are used for cancer treatment. Aim of the
present study is to investigate the phytochemical analysis and anti microbial activity of aqueous and
methanol extracts of Catharanthus roseus. The enzymatic and non enzymatic (DPPH) method was
employed to analyze the antioxidant property. Qualitative analysis of phytochemical screening
reveals the presence of Alkaloids, Phenol, Saponins and Protein. Further presents of phytochemicals
were detected by Thin Layer Chromatography (TLC), which is the standard technique for separating
organic compounds. The extracts were purified using Column chromatography (silica gel). The
fraction 3 was subjected to GC-MS analysis to the compounds presents in the extract.
Keywords: Catharanthus roseus, Phytochemical analysis, Antioxidant activity, Antibacterial activity.