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The mechanisms underlying the formation of different types of cancers and the different patterns of a
single type of cancer are of clinical importance in diagnosing the disease and also for therapy. In
epidemiological reports the intake of fatty diet has been ascribed to be an aetiological agent for
cancer development in general and very specifically to certain types of carcinomas like breast
(Mammary) adenocarcinoma. However, only a few studies have been made to contemplate the
compositional differences in the fatty acids, towards cancer prognosis. Recently it has been
substantiate that different fatty acids play a role either in enhancing or suppressing cancer
formation. In the light of the above studies, it is delineated and construed that there exists a
correlation between qualitative variation of essential fatty acids and the cancer manifestation. In the
present study the fatty acid composition of breast cancer was analyzed by gas chromatography to
substantiate their role in carcinogenesis. Metastatic breast cancer tissues were analyzed for the
compositional difference in their fatty acids by gas chromatography. The causative roles of nB6 type
essential fatty acids are discussed in the light of previous reports and evidences.
Keywords: Cancer, Metastatic breast cancer, Adenocarcinoma, Essential fatty acids