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This study deals with the effect of a common laundry detergent (Surf Excel Blue) on transamination in
liver of Heteropnustes fossilis Bloch on sub-lethal exposure to it.
Adult fishes of either sexes were reared in three different aquaria namely aquarium-I comprising Normal-
Control group, aquarium-II and III comprise Experimental groups of fishes exposed to 5 ppm and 10 ppm
of the detergent respectively. Prior to this the LC50 of this detergent for this species of fish was
experimentally evaluated as 22.51 ± 0.057 ppm. The treatment was done for 30 days in the months of
August and September, after which the study on the activities of two primary transaminases namely
Glutamate Oxaloacetate Transaminase (GOT) and Glutamate Pyruvate Transaminase (GPT), were done
in liver and blood-serum of both the Normal-Control and Experimental fishes. Estimation of the
important free amino acids was also done in liver homogenate of the fishes.
The study revealed that sub-lethal exposure to this detergent lead to significant alterations of these
transaminase activities and the process of transamination in liver of the experimental fishes.
Keywords: - Detergent, liver, transaminase, amino acid.