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Verotoxin is a toxin produced by some strain of Escherichia coli bacteria. Verotoxin also known as
Shiga-like toxin. Two types are of Verotoxin are known as SLT1 and SLT2. The Verotoxin or Shigalike
toxin associated with hemolytic-uremic syndrome in human. This toxin is a multi-subunit protein
made up one molecule of A subunit responsible for the toxic action, while other five molecules of the
B unit responsible for binding to a specific cell’s receptor. Present study is being performed towards
understand and structure prediction of this toxic protein. Verotoxin structures of both subunits are
being predicted through homology modeling. Three dimensional structures are being predicted and
validate through various online modeling tools and server.
Keyword: Protein modeling, Structure prediction, Toxic protein, in silico, validation.